報告題目：Constitutive activation of cellular immunity underlies the evolution of resistance to infection in Drosophila 報告人：Frank Jiggins教授，英國劍橋大學 (University of Cambridge) 時間：2020年12月16日 16:00-17:30 地點：騰訊會議ID：378 585 664 聯系人：曹川 18710164086 報告人簡介: 劍橋遺傳系教授，獲得劍橋大學本科、博士學位，2000-2003年Emmanuel College Research Fellow，2003-2008在Wellcome Trust、Royal Society資助下于愛丁堡大學進化生物學研究所工作，2009年回到劍橋大學遺傳系。擔任PLoS Pathogens, BMC Biology, eLife (Guest), Molecular Ecology等雜志編輯以及NERC Large Grant，Newton Fellowship等基金會評審成員。研究獲得英國生物技術與生物科學基金會 (BBSRC)、自然環境研究理事會(NERC)、惠康基金 (Wellcome Trust)、英國皇家學會 (Royal Society)、歐洲萊弗休姆基金 (Leverhulme Trust)等機構資助。目前主要研究工作包括昆蟲寄主與寄生生物之間的進化關系，探索影響寄主抗性的遺傳多樣性及其在自然種群中維持的機制。 部分代表作： Selected Publications Leit?o, AB, Bian, X, Day, JP, Pitton, S, Demir, E, Jiggins, FM 2019 Independent effects on cellular and humoral immune responses underlie genotype-by-genotype interactions between Drosophila and parasitoids. PLoS Pathogens. 15: e1008084. Martinez J, Klasson L, Welch JJ, Jiggins FM. 2020. Life and Death of Selfish Genes: Comparative Genomics Reveals the Dynamic Evolution of Cytoplasmic Incompatibility. Mol. Biol. Evol. Lewis S, Ross L, Bain SA, Pahita E, Smith SA, Cordaux R, Miska EA, Lenhard B, Jiggins FM 2020. Widespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropods. PLoS Genetics. Alves, JM, Carneiro, M, Cheng, JY, Lemos de Matos, A, Rahman, MM, Loog, L, Campos, PF, Wales, N, Eriksson, A, Manica, A, Strive, T, Graham, SC, Afonso, S, Bell, DJ, Belmont, L, Day, JP, Fuller, SJ, Marchandeau, S, Palmer, WJ, Queney, G, Surridge, AK, Vieira, FG, McFadden, G, Nielsen, R, Gilbert, MTP, Esteves, PJ, Ferrand, N and Jiggins, FM 2019 Parallel adaptation of rabbit populations to myxoma virus. Science. 363: 1319–1326 doi: 101126/scienceaau7285 Duxbury, EML, Day, JP, Vespasiani, DM, Thüringer, Y, Tolosana, I, Smith, SCL, Tagliaferri, L, Kamacioglu, A, Lindsley, I, Love, L, Unckless, RL, Jiggins, FM*, Longdon, B* 2019 Host-pathogen coevolution increases genetic variation in susceptibility to infection. eLife. Lewis, SH, Quarles, KA, Yang, Y, Tanguy, M, Frezal, L, Smith, SA, Sharma, SP, Cordaux, R, Gilbert, C, Giraud, I, Collins, DH, Zamore, PD, Miska, EA, Sarkies, P, Jiggins, FM 2017 Pan-arthropod analysis reveals somatic piRNAs as an ancestral defence against transposable elements. Nature Ecology and Evolution. 2: 174
|
